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Elizabeth Boskey, Ph.D.

The HPV Vaccine in Men

By February 17, 2011

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One of the big debates about using the HPV vaccine in men has had to do with the fact that it's mostly been promoted as an anti-cancer vaccine. Although HPV related cancers - such as rectal, throat and, penile cancers - do affect men, they are not generally considered to be as big an issue as cervical cancer is in women. Furthermore, many of these cancers are more common in men who have sex with men, a category which many parents - rightly or wrongly - do not think contains their sons. Thus, the benefits of the vaccine for young men have largely been seen as indirect - protecting their partners - even though they should see some direct benefits as well.

These direct benefits were recently confirmed by the publication of the results of a large Phase III vaccine trial of Gardasil in 16-26 year old men. The study, which appeared in the February 3 issue of the New England Journal of Medicine, found that Gardasil was quite effective in reducing genital warts in men who had not been previously exposed to the covered types of HPV. This adds to the evidence which, only last month, led to the FDA approval of the vaccine for preventing anal cancer in both men and women.

Right now, universal vaccination of young men is unlikely to be recommended for a variety of reasons - including the fact that the vaccine is expensive and vaccination simply may not be a cost effective solution to HPV related health problems. Still, there is a growing amount of evidence that HPV vaccination may be, at least, worth talking about with your teenage sons. If nothing else, doing so may be a good way to initiate important discussions of safe sex.

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June 17, 2011 at 12:30 am
(1) Louise Sacco says:

I was kind of wandering about this too. If HPV affects both men and women, why don’t they get vaccinated as well? I read on Reader’s Digest about a man who has HPV and is now battling neck cancer. It would be great if the male population could protect themselves from HPV too.

I know of a woman who has HPV but hers is the genital warts strain. Thank goodness there are treatments out there conveniently available like ZeroWarts. At least she can order online (www.zerowarts.co.uk) instead of buying it personally in pharmacies under the scrutiny of strangers.

March 28, 2013 at 9:46 pm
(2) John says:

What’s scary for me is that I had never even heard of this and I consider myself quite widely read (obviously not). This is a subject I think needs pushing out to a wider audience and I will certainly be making sure my 2 sons are educated about HPV.

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