In May 2012, the FDA approved the single-tablet combination medication Truvada for use in people at high risk for HIV transmission through sexual contact. However, although PreP can be effective when used properly, it should not be seen as a substitute for condoms, when they are a reasonable option.
Okwundu CI, Okoromah CA. (2009) "Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals." Cochrane Database Syst Rev.(1):CD007189.