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Is injection site pain one of the HPV vaccine side effects?

By Elizabeth Boskey, Ph.D., About.com

Updated May 06, 2009

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

Allison Michael Orenstein
Question: Is injection site pain one of the HPV vaccine side effects?
Answer:

Injection site pain can indeed be a side effect of the HPV vaccine. Although by no means will everyone experience it, it is the most commonly reported of the HPV vaccine side effects. Almost 20% of people receiving the vaccine report injection site pain, and the actual prevalence of at least some discomfort at the site is probably somewhat higher.

I experienced this type of discomfort first-hand when I received the first shot of the Gardasil vaccine series. I could actually feel the injection as it went into my arm. It was painful -- not horribly so, but noticeably. Fortunately, my arm stopped hurting within 15 minutes of getting the HPV vaccine.

Personally I found injection pain, as one of the HPV vaccine side effects, to be no big deal, but it is useful to know that it's a possibility to expect if you're headed to your doctor's office for the vaccine.

Sources:
Tucker, ME (2007)"Injection Site Pain Is Top Adverse Event for Gardasil" Skin & Allergy News 38(4):8

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